rs77413521

This is a intron variant variant in the DNAAF10 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

osteoarthritis, hip

Hatzikotoulas K et al. “Translational genomics of osteoarthritis in 1,962,069 individuals.” Nature 641(8065):1217-1224 (2025)

Allele A

OR 1.06

p 3.0e-9

N 1,152,707

Large GWAS

multi-ancestry

About DNAAF10

This gene encodes a protein with two WD40 repeat domains thought to be involved in an apoptosis via activation of caspase-3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

View all DNAAF10 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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