rs7741741
This is a regulatory region variant variant in the ADGRG6 gene.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
body weight
Jee YH et al. “Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures.” Nature Communications 16(1):4935 (2025)
Allele A
OR 0.01
p 2.0e-29
N 928,679
Large GWAS
multi-ancestry
body height
Berndt SI et al. “Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.” Nature Genetics 45(5):501-12 (2013)
Allele T
OR 1.24
p 1.0e-20
N 16,196
Meta-analysisLarge GWAS
European
Chiou JS et al. “Your height affects your health: genetic determinants and health-related outcomes in Taiwan.” Bmc Medicine 20(1):250 (2022)
Allele T
OR 0.04
p 3.0e-17
N 67,452
Large GWAS
East Asian
adolescent idiopathic scoliosis
Kou I et al. “Genome-wide association study identifies 14 previously unreported susceptibility loci for adolescent idiopathic scoliosis in Japanese.” Nature Communications 10(1):3685 (2019)
Allele A
OR 1.21
p 1.0e-17
N 38,683
Large GWAS
East Asian
About ADGRG6
This gene, which is upregulated in human umbilical vein endothelial cells, encodes a G protein-coupled receptor. Variations in this gene can affect a person's stature. Multiple transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Mar 2009]
View all ADGRG6 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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