rs7749040
This is a regulatory region variant variant in the AIG1 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Inguinal hernia
Wei J et al. “Identification of fifty-seven novel loci for abdominal wall hernia development and their biological and clinical implications: results from the UK Biobank.” Hernia : the Journal of Hernias and Abdominal Wall Surgery 26(1):335-348 (2022)
Allele T
OR 1.08
p 9.0e-13
N 275,546
Major Consortium StudyLarge GWAS
European
carotid artery thickness
Yeung MW et al. “Twenty-Five Novel Loci for Carotid Intima-Media Thickness: A Genome-Wide Association Study in >45 000 Individuals and Meta-Analysis of >100 000 Individuals.” Arteriosclerosis, Thrombosis, and Vascular Biology 42(4):484-501 (2022)
Allele T
OR 0.00
p 2.0e-9
N 100,253
Meta-analysisLarge GWAS
multi-ancestry
About AIG1
Enables hydrolase activity. Involved in long-chain fatty acid catabolic process. Located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all AIG1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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