rs77610730
This variant is located in the SNX8 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
plasminogen activator inhibitor 1 measurement
McCartney DL et al. “Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging.” Genome Biology 22(1):194 (2021)
Allele G
OR 2268.75
p 5.0e-28
N 6,149
Large GWAS
African American or Afro-Caribbean
About SNX8
Enables identical protein binding activity and phosphatidylinositol binding activity. Involved in early endosome to Golgi transport and intracellular protein transport. Located in early endosome membrane and retromer complex. [provided by Alliance of Genome Resources, Jul 2025]
View all SNX8 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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