rs7761746

This is a synonymous variant in the OR5V1 gene — it does not change the protein's amino acid sequence.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

triglyceride measurement

Hebbar P et al. “Genome-wide association study identifies novel recessive genetic variants for high TGs in an Arab population.” Journal of Lipid Research 59(10):1951-1966 (2018)
Allele A
OR 6.07
p 1.0e-9
N 1,353
Large GWAS
Greater Middle Eastern (Middle Eastern, North African or Persian)

About OR5V1

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]

View all OR5V1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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