rs7812088
This is a intron variant variant in the ABCF2 gene.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
serum IgG glycosylation measurement
Klarić L et al. “Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases.” Science Advances 6(8):eaax0301 (2020)
Allele A
OR 0.25
p 2.0e-22
N 8,090
Large GWAS
European
N-glycan measurement
Sharapov S et al. “A genome-wide association study in 10,000 individuals links plasma N-glycome to liver disease and anti-inflammatory proteins.” Nature Communications 16(1):5525 (2025)
Allele A
OR 0.21
p 4.0e-17
N 10,172
Large GWAS
European
femoral neck bone mineral density
Estrada K et al. “Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.” Nature Genetics 44(5):491-501 (2012)
Allele A
OR —
β 0.050
p 7.0e-9
N 32,961
Meta-analysisLarge GWAS
multi-ancestry
About ABCF2
This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ATP-binding cassette proteins transport various molecules across extra- and intracellular membranes. Alterations in this gene may be involved in cancer progression. Related pseudogenes have been identified on chromosomes 3 and 7. [provided by RefSeq, Mar 2019]
View all ABCF2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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