rs7816345
▶GWAS Catalog Trait Associations (12)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (12)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
body height
Yengo L et al. “A saturated map of common genetic variants associated with human height.” Nature 610(7933):704-712 (2022)
Allele T
OR 0.01
p 1.0e-29
N 5,314,291
Large GWAS
European, Hispanic or Latin American, East Asian, African unspecified, South Asian
appendicular lean mass
Pei YF et al. “The genetic architecture of appendicular lean mass characterized by association analysis in the UK Biobank study.” Communications Biology 3(1):608 (2020)
Allele T
OR 0.03
p 6.0e-24
N 450,243
Major Consortium StudyLarge GWAS
European
non-dense area measurement, mammographic density measurement
Lindström S et al. “Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer risk.” Nature Communications 5:5303 (2014)
Allele T
OR 0.24
p 2.0e-23
N 7,600
Large GWAS
multi-ancestry
cholesterol to total lipids in very large VLDL percentage
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.02
p 3.0e-15
N 450,015
Large GWAS
multi-ancestry
cholesteryl esters to total lipids in very large VLDL percentage
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.02
p 1.0e-14
N 450,015
Large GWAS
multi-ancestry
breast size
Eriksson N et al. “Genetic variants associated with breast size also influence breast cancer risk.” Bmc Medical Genetics 13:53 (2012)
Allele T
OR 0.15
p 2.0e-14
N 16,175
Large GWAS
European
cholesteryl esters to total lipids in large VLDL percentage
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.02
p 2.0e-13
N 450,015
Large GWAS
multi-ancestry
cholesterol to total lipids in large VLDL percentage
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.02
p 3.0e-11
N 450,015
Large GWAS
multi-ancestry
triglyceride measurement
Graham SE et al. “The power of genetic diversity in genome-wide association studies of lipids.” Nature 600(7890):675-679 (2021)
Allele T
OR 0.01
p 4.0e-10
N 1,320,016
Large GWAS
European
reticulocyte count
Vuckovic D et al. “The Polygenic and Monogenic Basis of Blood Traits and Diseases.” Cell 182(5):1214-1231.e11 (2020)
Allele T
OR 0.02
p 1.0e-9
N 408,112
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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