rs78228389

This is a intron variant variant in the FCRL6 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

serum amyloid P-component amount

Schmidt AF et al. “Genetic evidence for serum amyloid P component as a drug target in neurodegenerative disorders.” Open Biology 14(7):230419 (2024)

Allele A

OR 0.13

p 4.0e-9

N 44,228

Large GWAS

European

About FCRL6

Enables MHC class II protein binding activity and protein phosphatase binding activity. Predicted to be involved in cell surface receptor signaling pathway and immune response. Located in external side of plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all FCRL6 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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