rs7839059

This is a intergenic variant variant in the COLEC10 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

bone tissue density

Paternoster L et al. “Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure.” Plos Genetics 9(2):e1003247 (2013)
Allele A
OR 0.10
p 1.0e-10
N 5,878
Large GWAS
European

hip bone mineral density

Pei YF et al. “Association of 3q13.32 variants with hip trochanter and intertrochanter bone mineral density identified by a genome-wide association study.” Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the Usa 27(11):3343-3354 (2016)
Allele C
OR 0.10
p 7.0e-9
N 6,912
Large GWAS
multi-ancestry

About COLEC10

This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. The other members of this family are secreted proteins and bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. This gene product is a cytosolic protein, a characteristic that suggests that it may have different biological functions than other C-lectins. [provided by RefSeq, Jul 2008]

View all COLEC10 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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