rs7851693
This is a intron variant variant in the FUBP3 gene.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
femoral neck bone mineral density
Estrada K et al. “Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.” Nature Genetics 44(5):491-501 (2012)
Allele C
OR —
β 0.050
p 3.0e-22
N 32,961
Meta-analysisLarge GWAS
multi-ancestry
bone fracture
Trajanoska K et al. “Assessment of the genetic and clinical determinants of fracture risk: genome wide association and mendelian randomisation study.” Bmj (clinical Research Ed.) 362:k3225 (2018)
Allele G
OR 1.04
p 5.0e-19
N 264,973
Large GWAS
multi-ancestry
body weight
Jee YH et al. “Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures.” Nature Communications 16(1):4935 (2025)
Allele C
OR 0.01
p 2.0e-10
N 928,679
Large GWAS
multi-ancestry
About FUBP3
Enables single-stranded DNA binding activity. Involved in DNA-templated transcription; positive regulation of DNA-templated transcription; and positive regulation of gene expression. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Jul 2025]
View all FUBP3 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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