rs7870723

This is a intron variant variant in the HEMGN gene.

GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

platelet count

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele T
OR 0.04
p 2.0e-39
N 582,835
Major Consortium StudyLarge GWAS
multi-ancestry

serine protease 27 measurement

Allele C
OR 0.05
p 6.0e-33
N 47,745
Large GWAS
European

sortilin measurement

Allele C
OR 0.06
p 6.0e-32
N 47,745
Large GWAS
European

legumain measurement

Allele C
OR 0.05
p 9.0e-21
N 47,745
Large GWAS
European

About HEMGN

Predicted to be involved in regulation of osteoblast differentiation. Located in nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]

View all HEMGN variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Sign in to join the discussion.

Loading comments…