rs78781855
This is a intron variant variant in the STXBP4 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
aging, epigenetic status
Lu AT et al. “GWAS of epigenetic aging rates in blood reveals a critical role for TERT.” Nature Communications 9(1):387 (2018)
Allele G
OR 0.47
p 6.0e-9
N 8,393
Large GWAS
multi-ancestry
About STXBP4
Enables syntaxin binding activity. Involved in several processes, including positive regulation of cell cycle G1/S phase transition; positive regulation of keratinocyte proliferation; and protein stabilization. Located in extracellular exosome. [provided by Alliance of Genome Resources, Jul 2025]
View all STXBP4 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…