rs78947501
This is a intron variant variant in the TMEM131L gene.
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
level of tripeptidyl-peptidase 1 in blood
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele C
OR 0.13
p 1.0e-18
N 47,745
Large GWAS
European
platelet glycoprotein 4 level
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele C
OR 0.13
p 6.0e-17
N 47,745
Large GWAS
European
sialate O-acetylesterase measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele C
OR 0.12
p 3.0e-14
N 47,745
Large GWAS
European
platelet volume
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.09
p 5.0e-20
N 476,837
Major Consortium StudyLarge GWAS
multi-ancestry
About TMEM131L
Involved in negative regulation of canonical Wnt signaling pathway and negative regulation of immature T cell proliferation in thymus. Located in cytoplasm and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all TMEM131L variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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