rs7926971

This is a regulatory region variant variant in the TEAD1 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

retinal vasculature measurement

Jensen RA et al. “Novel Genetic Loci Associated With Retinal Microvascular Diameter.” Circulation. Cardiovascular Genetics 9(1):45-54 (2016)

Allele G

OR 0.05

p 3.0e-11

N 24,275

Large GWAS

multi-ancestry

body height

Lango Allen H et al. “Hundreds of variants clustered in genomic loci and biological pathways affect human height.” Nature 467(7317):832-8 (2010)

Allele A

OR —

β 0.023

p 4.0e-10

N 133,653

Large GWAS

European

About TEAD1

This gene encodes a ubiquitous transcriptional enhancer factor that is a member of the TEA/ATTS domain family. This protein directs the transactivation of a wide variety of genes and, in placental cells, also acts as a transcriptional repressor. Mutations in this gene cause Sveinsson's chorioretinal atrophy. Additional transcript variants have been described but their full-length natures have not been experimentally verified. [provided by RefSeq, May 2010]

View all TEAD1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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