rs793440

This variant is located in the FILIP1L gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

atrial fibrillation

Yuan S et al. “Cross-population GWAS and proteomics improve risk prediction and reveal mechanisms in atrial fibrillation.” Nature Communications 16(1):6426 (2025)

Allele T

OR 0.02

p 1.0e-10

N 1,840,341

Large GWAS

European

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ClinVar annotation

Benign

1 submitter

FILIP1L-related disorder

View on ClinVar →

About FILIP1L

Predicted to be involved in protein localization to actin cytoskeleton. Predicted to act upstream of or within several processes, including hindgut development; proteasomal protein catabolic process; and protein secretion. Predicted to be located in cytoplasm; membrane; and nucleus. Predicted to be active in actin cytoskeleton and centrosome. [provided by Alliance of Genome Resources, Jul 2025]

View all FILIP1L variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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