rs79354229
This is a intron variant variant in the COL21A1 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
gut microbiome measurement, breastfeeding duration
Stickley SA et al. “Gene-by-environment interactions modulate the infant gut microbiota in asthma and atopy.” The Journal of Allergy and Clinical Immunology 156(2):433-448 (2025)
Allele T
OR —
β 0.030
p 2.0e-8
N 693
Small GWAS
multi-ancestry
gut microbiome measurement, environmental exposure measurement
Stickley SA et al. “Gene-by-environment interactions modulate the infant gut microbiota in asthma and atopy.” The Journal of Allergy and Clinical Immunology 156(2):433-448 (2025)
Allele T
OR 0.03
p 2.0e-8
N 693
Small GWAS
multi-ancestry
About COL21A1
This gene encodes the alpha chain of type XXI collagen, a member of the FACIT (fibril-associated collagens with interrupted helices) collagen family. Type XXI collagen is localized to tissues containing type I collagen and maintains the integrity of the extracellular matrix. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
View all COL21A1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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