rs7938885

This variant is located in the NADSYN1 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

vitamin D level

Hong J et al. “Transethnic Evaluation Identifies Low-Frequency Loci Associated With 25-Hydroxyvitamin D Concentrations.” The Journal of Clinical Endocrinology and Metabolism 103(4):1380-1392 (2018)

Allele C

OR 8.13

p 5.0e-16

N 28,150

Large GWAS

multi-ancestry

About NADSYN1

Nicotinamide adenine dinucleotide (NAD) is a coenzyme in metabolic redox reactions, a precursor for several cell signaling molecules, and a substrate for protein posttranslational modifications. NAD synthetase (EC 6.3.5.1) catalyzes the final step in the biosynthesis of NAD from nicotinic acid adenine dinucleotide (NaAD).[supplied by OMIM, Apr 2004]

View all NADSYN1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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