rs7953704

This is a intron variant variant in the MLXIP gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

urate measurement

Gill D et al. “Urate, Blood Pressure, and Cardiovascular Disease: Evidence From Mendelian Randomization and Meta-Analysis of Clinical Trials.” Hypertension (dallas, Tex. : 1979) 77(2):383-392 (2021)

Allele A

OR 0.02

p 5.0e-23

N 454,183

Meta-analysisLarge GWAS

European

Köttgen A et al. “Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.” Nature Genetics 45(2):145-54 (2013)

Allele A

OR 0.03

p 3.0e-8

N 110,347

Large GWAS

European

About MLXIP

This gene encodes a protein that functions as part of a heterodimer to activate transcription. The encoded protein forms a heterodimer with Max-like protein X (MLX) and is involved in the regulation of genes in response to cellular glucose levels. [provided by RefSeq, Mar 2014]

View all MLXIP variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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