rs7971133

This is a intron variant variant in the R3HDM2 gene.

GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

urate measurement

Cho C et al. Large-scale cross-ancestry genome-wide meta-analysis of serum urate. Nature Communications 15(1):3441 (2024)
Allele T
OR 0.06
p 6.0e-110
N 1,029,323
Meta-analysisLarge GWAS
multi-ancestry

blood urea nitrogen amount

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.03
p 4.0e-20
N 598,949
Major Consortium StudyLarge GWAS
multi-ancestry

extracellular sulfatase Sulf-2 measurement

Sun BB et al. Genomic atlas of the human plasma proteome. Nature 558(7708):73-79 (2018)
Allele T
OR
β 0.230
p 5.0e-16
N 3,301
Large GWAS
European

About R3HDM2

Enables RNA binding activity. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Jul 2025]

View all R3HDM2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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