rs8016947
This is a regulatory region variant variant.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
psoriasis
Tsoi LC et al. “Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.” Nature Genetics 44(12):1341-8 (2012)
Allele G
OR 1.16
p 3.0e-17
N 33,394
Large GWAS
European
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele G
OR 0.14
p 1.0e-12
N 394,626
Large GWAS
European
Yin X et al. “Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility.” Nature Communications 6:6916 (2015)
Allele G
OR 1.19
p 2.0e-10
N 13,816
Meta-analysisLarge GWAS
multi-ancestry
Strange A et al. “A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.” Nature Genetics 42(11):985-990 (2010)
Allele G
OR 1.19
p 2.0e-11
N 7,353
Large GWAS
European
psoriasis, type 2 diabetes mellitus
Patrick MT et al. “Causal Relationship and Shared Genetic Loci between Psoriasis and Type 2 Diabetes through Trans-Disease Meta-Analysis.” The Journal of Investigative Dermatology 141(6):1493-1502 (2021)
Allele G
OR 1.08
p 9.0e-14
N 925,490
Meta-analysisLarge GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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