rs8027714

This is a intergenic variant variant.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Research that mentions this SNP (1)

Collagen XVIII and LOXL-4 polymorphisms in women with and without advanced pelvic organ prolapse
AssociationN=532Renata G. M. dos Santos et al.(2018)· International Urogynecology Journal

A case-control study of 532 postmenopausal Brazilian women examining rs2236479 (COL18A1) and rs2862296 (LOXL-4) polymorphisms for association with advanced pelvic organ prolapse (POP). No significant associations were found between either polymorphism and POP (COL18A1 AA: OR=0.69, 95% CI 0.41-1.17; LOXL-4 GG: OR=0.76, 95% CI 0.43-1.35). Age (OR=1.10), number of vaginal deliveries (OR=1.66), and family history (OR=2.55) were identified as independent risk factors for POP.

Traits studied:Pelvic organ prolapseUrinary incontinence

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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