rs8070454

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

granulocyte count

McCartney DL et al. “Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging.” Genome Biology 22(1):194 (2021)

Allele T

OR 0.01

p 3.0e-18

N 34,470

Large GWAS

European

level of phosphatidylcholine

Harshfield EL et al. “Genome-wide analysis of blood lipid metabolites in over 5000 South Asians reveals biological insights at cardiometabolic disease loci.” Bmc Medicine 19(1):232 (2021)

Allele T

OR 0.07

p 9.0e-13

N 13,814

Large GWAS

European

body mass index

Huang J et al. “Genomics and phenomics of body mass index reveals a complex disease network.” Nature Communications 13(1):7973 (2022)

Allele C

OR 0.01

p 3.0e-12

N 1,122,049

Large GWAS

European

Sidorenko J et al. “Genetic architecture reconciles linkage and association studies of complex traits.” Nature Genetics 56(11):2352-2360 (2024)

Allele C

OR 0.01

p 1.0e-9

N 650,000

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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