rs8072510

This is a stop gained variant in the SLFN13 gene.

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Research that mentions this SNP (1)

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Pilot screening study of targeted genetic polymorphisms for association with seasonal influenza hospital admission
AssociationN=14,471Tonia C. Carter et al.(2018)· Journal of Medical Virology

This pilot screening study evaluated 32 SNPs in viral immune response genes for association with hospitalized seasonal influenza in adults of European ancestry using a discovery group (26 cases, 993 controls) and two validation groups (84 cases, 4,076 controls; 128 cases, 9,187 controls). The study failed to replicate the previously reported association between IFITM3 rs12252 and hospitalized influenza (P > 0.05), and a preliminary finding of association with SLFN13 rs8072510 (P = 0.0099 in discovery group) was not confirmed in validation groups.

Traits studied:Hospitalized seasonal influenzaInfluenza hospital admissionSevere influenza infection
PubMedDOIMetascience Observatory

About SLFN13

Enables RNA endonuclease activity. Involved in rRNA catabolic process and tRNA decay. Located in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]

View all SLFN13 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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