rs8187735

This variant is located in the SLC18A3 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Hodgkins lymphoma

Osman Y et al. “Functional multigenic variations associated with hodgkin lymphoma.” International Journal of Laboratory Hematology 43(6):1472-1482 (2021)

Allele A

OR —

β 0.039

p 4.0e-11

N 97

Small GWAS

Greater Middle Eastern (Middle Eastern, North African or Persian)

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ClinVar annotation

Uncertain Significance★★★☆

4 submitters2 publications

Congenital myasthenic syndrome 21; not provided; Inborn genetic diseases

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About SLC18A3

This gene is a member of the vesicular amine transporter family. The encoded transmembrane protein transports acetylcholine into secretory vesicles for release into the extracellular space. Acetylcholine transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransferase gene. [provided by RefSeq, Jul 2008]

View all SLC18A3 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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