rs843005
This is a intron variant variant in the GC gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
vitamin D level
Hong J et al. “Transethnic Evaluation Identifies Low-Frequency Loci Associated With 25-Hydroxyvitamin D Concentrations.” The Journal of Clinical Endocrinology and Metabolism 103(4):1380-1392 (2018)
Allele T
OR 7.10
p 1.0e-12
N 28,150
Large GWAS
multi-ancestry
About GC
The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
View all GC variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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