rs860001

This is a intron variant variant in the CALN1 gene.

GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

body weight

Allele A
OR 0.02
p 4.0e-16
N 928,679
Large GWAS
multi-ancestry

waist circumference

Allele T
OR 0.01
p 1.0e-11
N 394,642
Large GWAS
European

body mass index

Sakaue S et al. A cross-population atlas of genetic associations for 220 human phenotypes. Nature Genetics 53(10):1415-1424 (2021)
Allele T
OR 0.01
p 2.0e-8
N 523,818
Large GWAS
multi-ancestry

About CALN1

This gene encodes a protein with high similarity to the calcium-binding proteins of the calmodulin family. The encoded protein contains two EF-hand domains and potential calcium-binding sites. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]

View all CALN1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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