rs869329
This variant is located in the MTAP gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
citrus intake measurement, melanoma
Marley AR et al. “Citrus-Gene interaction and melanoma risk in the UK Biobank.” International Journal of Cancer 150(6):976-983 (2022)
Allele A
OR —
p 2.0e-10
N 194,859
Major Consortium StudyLarge GWAS
European
About MTAP
This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage pathway of both adenine and methionine. The encoded enzyme is deficient in many cancers. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2021]
View all MTAP variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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