rs881375
This is a regulatory region variant variant in the PHF19 gene.
▶Research that mentions this SNP (1)
▶TRAF1 polymorphisms associated with rheumatoid arthritis susceptibility in Asians and in CaucasiansAssociationN=2,322Tae‐Un Han et al.(2009)· Arthritis & Rheumatism
A case-control association study of 1,316 Korean RA patients and 1,006 controls found that rs7021206 in TRAF1 intron 3 is significantly associated with rheumatoid arthritis susceptibility (OR 1.21, P = 0.0037), while rs3761847, which is associated with RA in Caucasians, showed no association in Koreans due to different linkage disequilibrium patterns. Fine-mapping identified a 66-kb haplotype region spanning TRAF1 containing variants associated with RA across both Asian and Caucasian populations.
About PHF19
Enables methylated histone binding activity. Involved in negative regulation of gene expression, epigenetic. Located in ESC/E(Z) complex. [provided by Alliance of Genome Resources, Apr 2025]
View all PHF19 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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