rs886477

This is a intron variant variant in the RPH3A gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

pulse pressure measurement

Takeuchi F et al. “Interethnic analyses of blood pressure loci in populations of East Asian and European descent.” Nature Communications 9(1):5052 (2018)

Allele A

OR 0.30

p 1.0e-8

N 130,777

Large GWAS

multi-ancestry

uric acid measurement

Cho SK et al. “Polygenic analysis of the effect of common and low-frequency genetic variants on serum uric acid levels in Korean individuals.” Scientific Reports 10(1):9179 (2020)

Allele A

OR 0.12

p 4.0e-8

N 6,881

Large GWAS

East Asian

About RPH3A

The protein encoded by this gene is thought to be an effector for RAB3A, which is a small G protein that acts in the late stages of neurotransmitter exocytosis. The encoded protein may be involved in neurotransmitter release and synaptic vesicle traffic. [provided by RefSeq, Dec 2016]

View all RPH3A variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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