rs890725875
This variant is located in the HPSE2 gene.
▶ClinVar annotation
Likely Benign★☆☆☆
1 submitter1 publicationAbout HPSE2
This gene encodes a heparanase enzyme. The encoded protein is a endoglycosidase that degrades heparin sulfate proteoglycans located on the extracellular matrix and cell surface. This protein may be involved in biological processes involving remodeling of the extracellular matrix including angiogenesis and tumor progression. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
View all HPSE2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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