rs896947430

This is a stop gained variant in the CC2D2A gene.

ClinVar annotation

Pathogenic★★★
8 submitters5 publications

CC2D2A-related disorder; Familial aplasia of the vermis; Meckel-Gruber syndrome; Retinitis pigmentosa 93

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About CC2D2A

This gene encodes a coiled-coil and calcium binding domain protein that appears to play a critical role in cilia formation. Mutations in this gene cause Meckel syndrome type 6, as well as Joubert syndrome type 9. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]

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Gene information from NCBI Gene. Variant classifications from ClinVar.

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