rs916264
This is a intron variant variant in the APOL2 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
aging, epigenetic status
Luo A et al. “Epigenetic aging is accelerated in alcohol use disorder and regulated by genetic variation in APOL2.” Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology 45(2):327-336 (2020)
Allele A
OR 3.09
p 5.0e-8
N 310
Small GWAS
multi-ancestry
About APOL2
This gene is a member of the apolipoprotein L gene family. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids or allow the binding of lipids to organelles. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
View all APOL2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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