rs922002208
This variant is located in the PCCA gene.
▶ClinVar annotation
About PCCA
The protein encoded by this gene is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. PCCA encodes the biotin-binding region of this enzyme. Mutations in either PCCA or PCCB (encoding the beta subunit) lead to an enzyme deficiency resulting in propionic acidemia. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]
View all PCCA variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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