rs925013
This variant is located in the LOC105372441 gene.
▶Research that mentions this SNP (1)
▶A comprehensive resequence analysis of the KLK15–KLK3–KLK2 locus on chromosome 19q13.33MethodsN=78Hemang Parikh et al.(2010)· Human Genetics
A comprehensive resequencing analysis of the KLK15-KLK3-KLK2 locus on chromosome 19q13.33 in 78 individuals of European ancestry using 454 next-generation sequencing. The authors identified 555 polymorphic loci including 116 novel SNPs and 182 novel insertion/deletion polymorphisms. They discovered 11 coding variants in KLK3 (5 non-synonymous, 1 frameshift), 4 in KLK15, and 5 in KLK2. The key SNP rs2735839 lies in a region of relatively low linkage disequilibrium; two markers (rs2569735, rs1058205) in high LD (r²≥0.8) with rs2735839 were identified. This catalog of common genetic variation provides a foundation for fine-mapping studies of prostate cancer susceptibility and PSA regulation.
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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