rs925098
This variant is located in the LCORL gene.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
birth weight
Horikoshi M et al. “Genome-wide associations for birth weight and correlations with adult disease.” Nature 538(7624):248-252 (2016)
Allele G
OR 0.03
p 1.0e-15
N 142,558
Large GWAS
multi-ancestry
body height
Graff M et al. “Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry.” American Journal of Human Genetics 108(4):564-582 (2021)
Allele G
OR 0.05
p 3.0e-13
N 41,389
Large GWAS
multi-ancestry
Carty CL et al. “Genome-wide association study of body height in African Americans: the Women's Health Initiative SNP Health Association Resource (SHARe).” Human Molecular Genetics 21(3):711-20 (2012)
Allele G
OR 0.06
p 3.0e-14
N 8,149
CohortLarge GWAS
African American or Afro-Caribbean
sex hormone-binding globulin measurement
Ruth KS et al. “Using human genetics to understand the disease impacts of testosterone in men and women.” Nature Medicine 26(2):252-258 (2020)
Allele G
OR 0.01
p 8.0e-9
N 189,473
Large GWAS
European
About LCORL
This gene encodes a transcription factor that appears to function in spermatogenesis. Polymorphisms in this gene are associated with measures of skeletal frame size and adult height. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
View all LCORL variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…