rs9270599

This is a upstream gene variant variant.

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

blood protein amount

Orrù V et al. “Complex genetic signatures in immune cells underlie autoimmunity and inform therapy.” Nature Genetics 52(10):1036-1045 (2020)

Allele A

OR 0.56

p 3.0e-65

N 3,060

Large GWAS

European

IGA glomerulonephritis

Li M et al. “Identification of susceptibility loci and relevant cell type for IgA nephropathy in Han Chinese by integrative genome-wide analysis.” Frontiers of Medicine 18(5):862-877 (2024)

Allele A

OR 1.55

p 4.0e-28

N 14,033

Large GWAS

East Asian

Alzheimer disease, peptic ulcer disease

Adewuyi EO et al. “A large-scale genome-wide cross-trait analysis reveals shared genetic architecture between Alzheimer's disease and gastrointestinal tract disorders.” Communications Biology 5(1):691 (2022)

Allele G

OR —

p 9.0e-9

N 911,585

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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