rs9276977
This variant is located in the HLA-DOA gene.
About HLA-DOA
HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. [provided by RefSeq, Jul 2008]
View all HLA-DOA variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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