rs9296404
This is a upstream gene variant variant in the CNPY3-GNMT gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
homocysteine measurement
Williams SR et al. “Genome-wide meta-analysis of homocysteine and methionine metabolism identifies five one carbon metabolism loci and a novel association of ALDH1L1 with ischemic stroke.” Plos Genetics 10(3):e1004214 (2014)
Allele T
OR 0.36
p 2.0e-63
N 4,810
Meta-analysis
multi-ancestry
About CNPY3-GNMT
This locus represents naturally occurring readthrough transcription between the upstream CNPY3 (canopy FGF signaling regulator 3) and the downstream GNMT (glycine N-methyltransferase) genes. Readthrough transcripts may encode proteins that have amino acid similarity with proteins encoded by both individual genes. [provided by RefSeq, Jan 2016]
View all CNPY3-GNMT variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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