rs934012

GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

ascending aorta diameter

Pirruccello JP et al. The Genetic Determinants of Aortic Distention. Journal of the American College of Cardiology 81(14):1320-1335 (2023)
Allele A
OR 0.08
p 9.0e-40
N 38,372
Large GWAS
European, NR
Pirruccello JP et al. Deep learning enables genetic analysis of the human thoracic aorta. Nature Genetics 54(1):40-51 (2022)
Allele A
OR 0.08
p 3.0e-37
N 33,637
Large GWAS
European

pulse pressure measurement

Yang ML et al. Sex-specific genetic architecture of blood pressure. Nature Medicine 30(3):818-828 (2024)
Allele A
OR 0.03
p 7.0e-34
N 349,328
Large GWAS
multi-ancestry

diastolic blood pressure change measurement

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele A
OR 0.03
p 2.0e-25
N 609,486
Major Consortium StudyLarge GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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