rs9356744
This is a intron variant variant in the CDKAL1 gene.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Drugs used in diabetes use measurement
Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)
Allele C
OR 0.16
p 5.0e-59
N 178,726
Large GWAS
East Asian
body mass index
Wen W et al. “Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index.” Human Molecular Genetics 23(20):5492-504 (2014)
Allele T
OR 0.04
p 5.0e-13
N 86,739
Meta-analysisLarge GWAS
multi-ancestry
Wen W et al. “Meta-analysis identifies common variants associated with body mass index in east Asians.” Nature Genetics 44(3):307-11 (2012)
Allele T
OR 3.39
p 2.0e-11
N 27,715
Meta-analysisLarge GWAS
multi-ancestry
glucose measurement
Karjalainen MK et al. “Genome-wide characterization of circulating metabolic biomarkers.” Nature 628(8006):130-138 (2024)
Allele T
OR 0.03
p 8.0e-10
N 136,016
Large GWAS
multi-ancestry
About CDKAL1
The protein encoded by this gene is a member of the methylthiotransferase family. The function of this gene is not known. Genome-wide association studies have linked single nucleotide polymorphisms in an intron of this gene with susceptibilty to type 2 diabetes. [provided by RefSeq, May 2010]
View all CDKAL1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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