rs9389985

This variant is located in the ADGRG6 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

adolescent idiopathic scoliosis

Kou I et al. “Genome-wide association study identifies 14 previously unreported susceptibility loci for adolescent idiopathic scoliosis in Japanese.” Nature Communications 10(1):3685 (2019)

Allele G

OR 1.21

p 4.0e-20

N 79,211

Large GWAS

East Asian

About ADGRG6

This gene, which is upregulated in human umbilical vein endothelial cells, encodes a G protein-coupled receptor. Variations in this gene can affect a person's stature. Multiple transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Mar 2009]

View all ADGRG6 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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