rs939335

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

beta-citrylglutamate measurement

Hysi PG et al. “Metabolome Genome-Wide Association Study Identifies 74 Novel Genomic Regions Influencing Plasma Metabolites Levels.” Metabolites 12(1) (2022)
Allele G
OR 0.23
p 7.0e-51
N 8,809
Large GWAS
European
Yin X et al. “Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci.” Nature Communications 13(1):1644 (2022)
Allele G
OR 0.23
p 8.0e-34
N 6,136
Large GWAS
European

platelet component distribution width

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele G
OR 0.02
p 3.0e-24
N 394,642
Large GWAS
European
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Research that mentions this SNP (1)

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Allelic variants in HTR3C show association with autism
AssociationN=356Karola Rehnström et al.(2009)· American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

A family-based association study of 97 Finnish families with autistic disorder tested 125 SNPs in 11 candidate genes at 3q25-27, a linkage region for autism. Two nonsynonymous SNPs in HTR3C (rs6766410, N163K and rs6807362, G405A) showed significant association (P = 0.0012), with the C-C haplotype overtransmitted to affected individuals (P = 0.006). The study proposes HTR3C as a novel candidate gene for autism spectrum disorders.

Traits studied:Autism spectrum disordersAutistic disorder
PubMedDOIMetascience Observatory

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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