rs942065

This is a intron variant variant in the UNC79 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

gastroesophageal reflux disease

Ong JS et al. “Multitrait genetic association analysis identifies 50 new risk loci for gastro-oesophageal reflux, seven new loci for Barrett's oesophagus and provides insights into clinical heterogeneity in reflux diagnosis.” Gut 71(6):1053-1061 (2022)

Allele G

OR —

β 0.031

p 8.0e-10

N 602,604

Large GWAS

European

About UNC79

The NALCN channel is responsible for Na(+) leak currents. The protein encoded by this gene, along with UNC80, is an accessory subunit of the NALCN channel that contributes to the Ca(2+) sensitivity of the channel. [provided by RefSeq, Sep 2016]

View all UNC79 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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