rs943382723

This variant is located in the FNDC3B gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

invasive mechanical ventilation

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 2.01
p 1.0e-11
N 621,300
Major Consortium StudyLarge GWAS
multi-ancestry

About FNDC3B

Enables RNA binding activity. Predicted to act upstream of or within several processes, including negative regulation of osteoblast differentiation; substrate adhesion-dependent cell spreading; and type II pneumocyte differentiation. Predicted to be located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Jul 2025]

View all FNDC3B variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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