rs9459805

This is a intron variant variant in the RNASET2 gene.

Research that mentions this SNP (1)

Genome-wide association study of endometrial cancer in E2C2
AssociationN=23,420Immaculata De Vivo et al.(2014)· Human Genetics

Genome-wide association study of endometrial cancer (7,077 cases, 16,343 controls) identifying replication of the known HNF1B locus (rs4430796, OR=0.82, P=4.3×10⁻¹¹) and a novel genome-wide significant association at the RNASET2 locus (rs9459805, OR=1.19, P=1.11×10⁻⁵). A suggestive locus at PRLR (prolactin receptor) was also identified.

Traits studied:Endometrial cancerEndometrioid endometrial cancerSerous endometrial cancer

About RNASET2

This ribonuclease gene is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement. [provided by RefSeq, Jul 2008]

View all RNASET2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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