rs9510787

This variant is located in the TNFRSF19 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

nasopharyngeal neoplasm

Bei JX et al. “A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci.” Nature Genetics 42(7):599-603 (2010)

Allele G

OR 1.20

p 2.0e-9

N 3,477

Large GWAS

East Asian

About TNFRSF19

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. This receptor is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

View all TNFRSF19 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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