rs9525638
This is a intergenic variant variant.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
bone tissue density
Medina-Gomez C et al. “Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects.” American Journal of Human Genetics 102(1):88-102 (2018)
Allele T
OR —
β 0.084
p 2.0e-10
N 11,807
Meta-analysisLarge GWAS
European, NR
Kemp JP et al. “Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment.” Plos Genetics 10(6):e1004423 (2014)
Allele T
OR 0.09
p 2.0e-8
N 9,416
Large GWAS
multi-ancestry
cortical thickness
Zheng HF et al. “WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk.” Plos Genetics 8(7):e1002745 (2012)
Allele T
OR 0.09
p 4.0e-9
N 5,878
Large GWAS
European
bone tissue density, lean body mass
Medina-Gomez C et al. “Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus.” Nature Communications 8(1):121 (2017)
Allele C
OR —
p 1.0e-8
N 10,414
Meta-analysisLarge GWAS
European, NR
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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