rs954976

This is a intron variant variant in the PLEKHA5 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

body mass index

Huang J et al. Genomics and phenomics of body mass index reveals a complex disease network. Nature Communications 13(1):7973 (2022)
Allele T
OR 0.01
p 7.0e-11
N 1,122,049
Large GWAS
European
Sidorenko J et al. Genetic architecture reconciles linkage and association studies of complex traits. Nature Genetics 56(11):2352-2360 (2024)
Allele T
OR 0.01
p 1.0e-10
N 650,000
Large GWAS
European

About PLEKHA5

Predicted to enable phosphatidylinositol phosphate binding activity. Predicted to act upstream of or within reproductive system development. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]

View all PLEKHA5 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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