rs9557704
This is a intron variant variant in the ITGBL1 gene.
▶Research that mentions this SNP (1)
▶Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women’s Health Initiative SHARe StudyAssociationN=11,687Digna R. Velez Edwards et al.(2013)· Human Genetics
A genome-wide gene-environment interaction study examined 8,203 African-American and 3,484 Hispanic postmenopausal women from the Women's Health Initiative SHARe GWAS for SNP interactions with lifestyle factors (smoking, diet, physical activity, alcohol) on BMI and waist-to-hip ratio. The strongest BMI gene-environment interaction across cohorts was rs10133840 with smoking (beta=-0.01, P=3.81×10^-7), and the strongest WHR interaction in African-Americans was rs9557704 (ITGBL1) with dietary energy intake (beta=-0.04, P=2.17×10^-7).
About ITGBL1
This gene encodes a beta integrin-related protein that is a member of the EGF-like protein family. The encoded protein contains integrin-like cysteine-rich repeats. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
View all ITGBL1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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