rs965808

This variant is located in the GNAS-AS1 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

body height

Yengo L et al. “A saturated map of common genetic variants associated with human height.” Nature 610(7933):704-712 (2022)

Allele C

OR 0.01

p 4.0e-20

N 5,314,291

Large GWAS

European, Hispanic or Latin American, East Asian, African unspecified, South Asian

DNA methylation

Rentería ME et al. “GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.” Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies 16(4):767-81 (2013)

Allele G

OR —

p 5.0e-9

N 256

Small GWAS

European

About GNAS-AS1

This gene produces a paternally-imprinted antisense RNA transcript that helps regulate the GNAS complex locus, which encodes the alpha subunit of the stimulatory G protein. Defects in this gene are a cause of pseudohypoparathyroidism type Ib.[provided by RefSeq, Jun 2010]

View all GNAS-AS1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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